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Review
. 2020 Aug;127(8):1127-1130.
doi: 10.1016/j.ophtha.2020.02.014. Epub 2020 Feb 20.

Post-antibiotic Ocular Surface Microbiome in Children: A Cluster-Randomized Trial

Thuy Doan  1 , Armin Hinterwirth  2 , Lee Worden  2 , Ahmed M Arzika  3 , Ramatou Maliki  3 , Cindi Chen  2 , Lina Zhong  2 , Zhaoxia Zhou  2 , Nisha R Acharya  4 , Travis C Porco  5 , Jeremy D Keenan  4 , Thomas M Lietman  5
Affiliations
Review

Post-antibiotic Ocular Surface Microbiome in Children: A Cluster-Randomized Trial

Thuy Doan et al. Ophthalmology. 2020 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Ocular surface bacterial composition and diversity of children randomized to the placebo and azithromycin-treated groups. A, Locations of villages randomized in the Dosso region of Niger. Black and red circles represent villages randomized to placebo and azithromycin, respectively (terrain base maps www.thunderforest.com; data, www.osm.org/copyright, adapted under CC-BY-SA 2.0). B, Mean relative abundance of the 15 most abundant genera at baseline and 24 months for 600 samples from 30 villages between treatment groups. C, Scatter plots for Shannon’s diversity index at baseline (P = 0.84) and at 24 months (P = 0.04). D, Density plot for inverse Simpson’s diversity index at baseline (P = 0.99) and at 24 months (P = 0.02). All P values are permuted with 10 000 simulations.
See this image and copyright information in PMC

References

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