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Review
. 2020 Mar-Apr;63(2):79-91.
doi: 10.1016/j.pcad.2020.03.006. Epub 2020 Mar 19.

ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research

Joyonna Carrie Gamble-George  1 , Christopher T Longenecker  2 , Allison R Webel  3 , David H Au  4 , Arleen F Brown  5 , Hayden Bosworth  6 , Kristina Crothers  7 , William E Cunningham  8 , Kevin A Fiscella  9 , Alison B Hamilton  10 , Christian D Helfrich  11 , Joseph A Ladapo  12 , Amneris Luque  13 , Jonathan N Tobin  14 , Gail E Wyatt  15 ; Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium
Affiliations
Review

ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research

Joyonna Carrie Gamble-George et al. Prog Cardiovasc Dis. 2020 Mar-Apr.

Abstract

Antiretroviral therapy (ART) prevented premature mortality and improved the quality of life among people living with the human immunodeficiency virus (PLWH), such that now more than half of PLWH in the United States are 50 years of age and older. Increased longevity among PLWH has resulted in a significant rise in chronic, comorbid diseases. However, the implementation of guideline-based interventions for preventing, treating, and managing such age-related, chronic conditions among the HIV population is lacking. The PRECluDE consortium supported by the Center for Translation Research and Implementation Science at the National Heart, Lung, and Blood Institute catalyzes implementation research on proven-effective interventions for co-occurring heart, lung, blood, and sleep diseases and conditions among PLWH. These collaborative research studies use novel implementation frameworks with HIV, mental health, cardiovascular, and pulmonary care to advance comprehensive HIV and chronic disease healthcare in a variety of settings and among diverse populations.

Keywords: Antiretroviral therapy; COPD; Cardiovascular disease; Comorbidities; HIV; Implementation science.

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Conflict of interest statement

Disclosures/Conflicts of Interest

There are no financial conflicts of interest to disclose. This work is supported in part by the National Institutes of Health (U01HL142099 (CL, AW, and HB), U01HL142107 (KF, AL, and JNT), U01HL142104 (JL and WC), U01HL142109 (AB, ABH, and GW), and U01HL142103 (KC, DHA, and CDH)).

Figures

Figure 1:
Figure 1:. Map of Study Sites in the PRECluDE Consortium.
The PRECluDE consortium extends over eleven geographical areas throughout the U.S. at more than 30 healthcare organizations.
See this image and copyright information in PMC

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