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Review
. 2019 Sep;13(3):120-131.

Premature Ejaculation: From Physiology to Treatment

Affiliations
Review

Premature Ejaculation: From Physiology to Treatment

Mário Pereira-Lourenço et al. J Family Reprod Health. 2019 Sep.

Abstract

Objective: To review in literature about the concept of premature ejaculation from physiology to treatment. Materials and methods: A literature search conducted with Pubmed and Cochrane. Results: An accurate clinical history is the best diagnostic method, and in the majority of the cases it is enough to differentiate between primary and acquired premature ejaculation. Nowadays the treatment is not curative but is effective in increasing the Intravaginal Ejaculatory Latency Time, improving the couple's sexual satisfaction. Conclusion: Although PE is the most frequent sexual dysfunction, it is still sub-diagnosed. Combining behavioural techniques with pharmacotherapy is the best way of treatment.

Keywords: Physiology; Premature Ejaculation; Sexual Dysfunction; Treatment.

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Figures

Figure 1
Figure 1
Central control of ejaculation and connections with medullar and peripheric control. Adapted from Clemet et al.    (3)

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References

    1. Parnham A, Serefoglu EC. Classification and definition of premature ejaculation. Transl Androl Urol. 2016;5:416–23. - PMC - PubMed
    1. Martin C, Nolen H, Podolnick J, Wang R. Current and emerging therapies in premature ejaculation: Where we are coming from, where we are going. Int J Urol. 2017;24:40–50. - PubMed
    1. Clement P, Giuliano F. Physiology and Pharmacology of Ejaculation. Basic Clin Pharmacol Toxicol. 2016;119(Suppl 3):18–25. - PubMed
    1. Educational Committee of the ESSM. The ESSM Manual of Sexual Medicine. 2nd updated ed. Medix; 2015.
    1. Brackett NL, Ferrell SM, Aballa TC, Amador MJ, Padron OF, Sonksen J, et al. An analysis of 653 trials of penile vibratory stimulation in men with spinal cord injury. J Urol. 1998;159:1931–4. - PubMed

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