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Randomized Controlled Trial
. 2020 Feb;32(1):67-81.
doi: 10.1521/aeap.2020.32.1.67.

Acceptability, Feasibility, and Preliminary Efficacy of a Resilience-Oriented Family Intervention to Prevent Adolescent HIV and Depression: A Pilot Randomized Controlled Trial

Caroline Kuo  1   2 , Catherine Mathews  3 , Danielle Giovenco  4 , Millicent Atujuna  5 , William Beardslee  6 , Jacqueline Hoare  7 , Dan J Stein  8 , Larry K Brown  9
Affiliations
Randomized Controlled Trial

Acceptability, Feasibility, and Preliminary Efficacy of a Resilience-Oriented Family Intervention to Prevent Adolescent HIV and Depression: A Pilot Randomized Controlled Trial

Caroline Kuo et al. AIDS Educ Prev. 2020 Feb.

Abstract

We tested the acceptability, feasibility, and preliminary efficacy of Our Family Our Future, a resilience-oriented intervention engaging families in prevention of adolescent HIV and depression. South African adolescents, 13-15 years of age, with mild depressive symptoms, were randomized to intervention or wait-list using parallel assignment in a single-blind trial. HIV risk behavior and depression were evaluated at baseline, 1, and 3 months. We examined intervention satisfaction, fidelity, trial retention, and preliminary efficacy. One hundred-ninety-six adolescent-parent dyads completed eligibility screening and baseline, and n = 73 dyads were randomized. All families ranked intervention quality as good or excellent. Over 90% were satisfied with content. Facilitators were adherent to intervention protocol. All families were retained in post-intervention assessments. Intervention recipients reported diminished depressive symptoms, inconsistent condom use, and sexual activity, as well as increased HIV testing. Our Family Our Future is highly acceptable and feasible and should be tested in a future efficacy trial.

Keywords: South Africa; depression; family intervention; prevention; resilience.

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Conflict of interest statement

Declarations of Interests: None

Figures

Figure 1.
Figure 1.
Consort Diagram for Pilot Randomized Controlled Trial of Our Family Our Future
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