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Comment
. 2020 Mar 1;143(3):716-718.
doi: 10.1093/brain/awaa055.

Proof-of-concept for a gene replacement approach to CDKL5 deficiency disorder

Tim A Benke  1   2 , Peter C Kind  3
Affiliations
Comment

Proof-of-concept for a gene replacement approach to CDKL5 deficiency disorder

Tim A Benke et al. Brain. .

Abstract

This scientific commentary refers to ‘Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder’, by Gao etal. (doi:10.1093/brain/awaa028).

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References

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    1. Gao Y, Irvine E, Eleftheriadou I, Jimenez Naranjo C, Bosch L, Glegola J, et al.Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder. Brain 2020; 143: 811–832. - PubMed
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Supplementary concepts