Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Mar 1;143(3):718-721.
doi: 10.1093/brain/awaa060.

Towards metabolic disconnection - symptom mapping

Stephanie J Forkel  1   2   3 , Michel Thiebaut de Schotten  1   2
Affiliations
Comment

Towards metabolic disconnection - symptom mapping

Stephanie J Forkel et al. Brain. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests statement: The authors report no competing interests.

Figures

Figure
Figure. The ‘hidden lesion’.
A) MRI-negative and PET-positive scans of the same patient (images courtesy of Jha et al.). B) Metabolic lesion-symptom map for phonemic verbal fluency as identified by Jha et al. C) Example of a structural lesion-symptom map for phonemic verbal fluency as obtained from Kinkingnéhun et al., 2007. D) Functional activation maps from healthy controls performing a verbal fluency task in an MRI scanner. Maps derived from Neurosynth (http://www.neurosynth.org/, Yarkoni et al., 2011). AG, angular gyrus; FG, fusiform gyrus; IFG, inferior frontal gyrus; ITG, inferior temporal gyrus; MFG, middle frontal gyrus, preSMA, presupplementary motor area.
See this image and copyright information in PMC

Comment on

References

    1. Bates E, Wilson S, Saygin AP, Dick F, Sereno M, Knight RT, Dronkers NF. Voxel-based lesion-symptom mapping. Nature Neuroscience. 2003;6(5):448–450. - PubMed
    1. Corbetta M, Kincade MJ, Lewis C, Snyder AZ, Sapir A. Neural Basis and Recovery of Spatial Attention Deficits in Spatial Neglect. Nat Neurosci. 2005;8(11):1603–10. - PubMed
    1. Forkel SJ, Catani M. Lesion mapping in acute stroke aphasia and its implications for recovery. Neuropsychologia. 2018;115:88–100. - PMC - PubMed
    1. Hillis AE, Newhart M, Heidler J, Barker PB, Herskovits EH, Degaonkar M. Anatomy of Spatial Attention: Insights from Perfusion Imaging and Hemispatial Neglect in Acute Stroke. Journal of Neuroscience. 2005;25(12):3161–3167. doi: 10.1523/JNEUROSCI.4468-04.200. - DOI - PMC - PubMed
    1. Jha, et al. Metabolic lesion–deficit mapping of human cognition. Brain. 2020 - PMC - PubMed

Publication types

LinkOut - more resources