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Editorial
. 2020 May;158(6):1538-1540.
doi: 10.1053/j.gastro.2020.03.027. Epub 2020 Mar 20.

Channelopathy of the Pancreas Causes Chronic Pancreatitis

Affiliations
Editorial

Channelopathy of the Pancreas Causes Chronic Pancreatitis

Miklós Sahin-Tóth. Gastroenterology. 2020 May.
No abstract available

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Conflict of interest statement

Conflict of interest: No conflicts to declare.

Figures

Figure 1.
Figure 1.
Hypothetical model of the ductal pathway of genetic risk in chronic pancreatitis. See text for details. Based on this model, it is intriguing to speculate that TRPV6 and CFTR might interact directly and affect each other’s function. Figure was modified from [1].

Comment on

References

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    1. Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, Masson E, Nakano E, Kakuta Y, Niihori T, Funayama R, Shirota M, Hirano T, Kawamoto T, Hosokoshi A, Kume K, Unger L, Ewers M, Laumen H, Bugert P, Mori MX, Tsvilovskyy V, Weißgerber P, Kriebs U, Fecher-Trost C, Freichel M, Diakopoulos KN, Berninger A, Lesina M, Ishii K, Itoi T, Ikeura T, Okazaki K, Kaune T, Rosendahl J, Nagasaki M, Uezono Y, Algül H, Nakayama K, Matsubara Y, Aoki Y, Férec C, Mori Y, Witt H, Shimosegawa T. Variants that affect function of calcium channel TRPV6 are associated with early-onset chronic pancreatitis. Gastroenterology 2020, 158:1626–1641 - PubMed
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