Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul-Aug:36:101632.
doi: 10.1016/j.tmaid.2020.101632. Epub 2020 Mar 20.

Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot

Sophie Amrane  1 , Hervé Tissot-Dupont  1 , Barbara Doudier  2 , Carole Eldin  3 , Marie Hocquart  2 , Morgane Mailhe  2 , Pierre Dudouet  2 , Etienne Ormières  2 , Lucie Ailhaud  2 , Philippe Parola  3 , Jean-Christophe Lagier  1 , Philippe Brouqui  1 , Christine Zandotti  4 , Laetitia Ninove  4 , Léa Luciani  4 , Céline Boschi  2 , Bernard La Scola  1 , Didier Raoult  1 , Matthieu Million  1 , Philippe Colson  1 , Philippe Gautret  5
Affiliations

Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot

Sophie Amrane et al. Travel Med Infect Dis. 2020 Jul-Aug.

Abstract

Background: Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases.

Method: We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples.

Results: Over our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63.

Conclusion: Early recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.

Keywords: COVID-19; Coronaviruses; Epidemic; Influenza; SARS-CoV-2; Travel.

PubMed Disclaimer

Conflict of interest statement

None to declare.

Figures

Fig. 1
Fig. 1
Definition of suspected COVID-19 cases overtime in France.
Fig. 2
Fig. 2
Numbers of patients by date of consultation.
Fig. 3
Fig. 3
Proportion of each virus among patients testing positive according to region of exposure.
See this image and copyright information in PMC

Comment in

References

    1. Zhu N., Zhang D., Wang W., Li X., Yang B., Song J. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. doi: 10.1056/NEJMoa2001017. - DOI - PMC - PubMed
    1. WHO Situation report coronavirus. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio... n.d., (accessed March 11, 2020)
    1. Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed
    1. Phan L.T., Nguyen T.V., Luong Q.C., Nguyen T.V., Nguyen H.T., Le H.Q. Importation and human-to-human transmission of a novel coronavirus in vietnam. N Engl J Med. 2020;382:872–874. doi: 10.1056/NEJMc2001272. - DOI - PMC - PubMed
    1. Santé publique France. Infection au nouveau Coronavirus (SARS-CoV-2), COVID-19, France et Monde n.d. https://www.santepubliquefrance.fr/maladies-et-traumatismes/maladies-et-....

MeSH terms