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. 2020 Mar;25(11):2000230.
doi: 10.2807/1560-7917.ES.2020.25.11.2000230.

Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020

Emanuele Nicastri  1   2 , Alessandra D'Abramo  1   2 , Giovanni Faggioni  3 , Riccardo De Santis  3 , Andrea Mariano  1 , Luciana Lepore  1 , Filippo Molinari  3 , Giancarlo Petralito  3 , Silvia Fillo  3 , Diego Munzi  3 , Angela Corpolongo  1 , Licia Bordi  1 , Fabrizio Carletti  1 , Concetta Castiletti  1 , Francesca Colavita  1 , Eleonora Lalle  1 , Nazario Bevilacqua  1 , Maria Letizia Giancola  1 , Laura Scorzolini  1 , Simone Lanini  1 , Claudia Palazzolo  1 , Angelo De Domenico  4 , Maria Anna Spinelli  3 , Paola Scognamiglio  1 , Paolo Piredda  4 , Raffaele Iacomino  4 , Andrea Mone  4 , Vincenzo Puro  1 , Nicola Petrosillo  1 , Antonio Battistini  5 , Francesco Vairo  1 , Florigio Lista  3   6 , Giuseppe Ippolito  1   6 ; INMI and the Italian Army COVID-19 study groups  7
Affiliations

Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020

Emanuele Nicastri et al. Euro Surveill. 2020 Mar.

Abstract

Data concerning the transmission of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) in paucisymptomatic patients are lacking. We report an Italian paucisymptomatic case of coronavirus disease 2019 with multiple biological samples positive for SARS-CoV-2. This case was detected using the World Health Organization protocol on cases and contact investigation. Current discharge criteria and the impact of extra-pulmonary SARS-CoV-2 samples are discussed.

Keywords: COVID-19; Italy; paucisymptomatic case.

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Conflict of interest statement

Conflict of interest: None declared.

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References

    1. Tan W, Zhao X, Ma X, Wang W, Niu P, Xu W, et al. A novel coronavirus genome identified in a cluster of pneumonia cases — Wuhan, China 2019−2020. China CDC Weekly. 2020;2:61-2. - PMC - PubMed
    1. European Centre for Disease Prevention and Control (ECDC). COVID-19. Situation update worldwide. Stockholm: ECDC. [Accessed 17 Mar 2020]. Available from: https://www.ecdc.europa.eu/en/geographical-distribution-2019-ncov-cases
    1. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507-13. 10.1016/S0140-6736(20)30211-7 - DOI - PMC - PubMed
    1. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020. [Epub ahead of print]. 10.1001/jama.2020.1585 - DOI - PMC - PubMed
    1. World Health Organization (WHO). The First Few X (FFX) Cases and contact investigation protocol for 2019-novel coronavirus (2019-nCoV) infection. Geneva: WHO; 29 Jan 2020. Available from: https://www.who.int/publications-detail/the-first-few-x-(ffx)-cases-and-...

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