Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1977 Mar 19;6(11):927-30.

[The relation between anti-hypertensive action and plasmatic concentration of pindolol. Preliminary study]

[Article in French]
Y Weiss, Y Loria, D Lavene, D Georges, M Safar, P Milliez
  • PMID: 322092
Clinical Trial

[The relation between anti-hypertensive action and plasmatic concentration of pindolol. Preliminary study]

[Article in French]
Y Weiss et al. Nouv Presse Med. .

Abstract

A correlation study between the antihypertensive effect and the plasma level of pindolol was performed in 10 patients with permanent essential hypertension. Pindolol was given orally (20 mg/day) during 9 days. The highly significant fall in blood pressure (delta SBP and delta DBP) is directly correlated negatively correlated, to the pretreatment pressure (p less than 0.02 for deltaSBP and p less than 0.05 deltaDBP) and negatively correlated to the pindolol plasma level (P less than 0.001 for delta SBP and p less than 0.05 for delta DBP). Multiple regression analysis shows, for delta SBP, a stronger influence of plasma level than of basal blood pressure. These results suggest that pindolol could have a specific effect in some hypertensive patients.

PubMed Disclaimer