Cardiolipin's Remodeling Rules Revealed: The Role of the Cellular Lipidome
- PMID: 32209457
- DOI: 10.1016/j.celrep.2020.03.010
Cardiolipin's Remodeling Rules Revealed: The Role of the Cellular Lipidome
Abstract
In this issue of Cell Reports, Oemer et al. (2020) define the acyl chain composition of cardiolipin and other lipid classes in murine tissues. They then employ artificial neural networks to predict mechanisms that govern cardiolipin tissue specificity, with implications for understanding cellular pathogenesis in human disease.
Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.
Comment on
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Phospholipid Acyl Chain Diversity Controls the Tissue-Specific Assembly of Mitochondrial Cardiolipins.Cell Rep. 2020 Mar 24;30(12):4281-4291.e4. doi: 10.1016/j.celrep.2020.02.115. Cell Rep. 2020. PMID: 32209484
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