A Neurovisceral Integrative Study on Cognition, Heart Rate Variability, and Fitness in the Elderly

Abstract

The association between physical fitness and cognitive performance has been widely investigated in the literature. However, the neurophysiological mechanisms underlying this relationship are not yet clear. Here, we aim to evaluate the interactions between executive function measures, heart rate variability (HRV), and physical fitness in the context of the neurovisceral integration (NVI) theory. Twenty-eight healthy elderly subjects (>60 years) were submitted to evaluation of executive performance with three computerized tests: the N-back test measured working memory capacity, the Stroop Color test evaluated inhibitory control and selective attention, and the Wisconsin Card Sorting Test (WCST) evaluated abstract reasoning and cognitive flexibility. We also used the Physical Testing Battery for the Elderly to measure aerobic capacity, dynamic balance, upper body flexibility, and handgrip strength. Our results confirm the relationship between executive function and physical fitness, particularly between working memory, cardiorespiratory fitness, and dynamic balance. We also demonstrate an association between executive performance and HRV in older people, corroborating previous results from other groups obtained in young adults. However, our regression models did not indicate that HRV mediates the relationship between cognition and physical fitness in the elderly, suggesting that age-related degeneration of autonomic control can affect aspects of NVI in this population.

Keywords: aging; autonomic nervous system; cognition; executive functions; heart rate variability; physical fitness; working memory.

Figure 1

Correlations between working memory, aerobic capacity, and dynamic balance. (A) Hits in 2-back level and walk, (B) total hits in N-back test and walk, (C) misses in N-back and walk, (D) total hits in N-back test and TUG, and (E) misses in N-back and walk.