Why is COVID-19 so mild in children?

Petter Brodin^{1

2}

Affiliations

¹ Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
² Unit of Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden.

Editorial

Petter Brodin. Acta Paediatr. 2020 Jun.

. 2020 Jun;109(6):1082-1083.

doi: 10.1111/apa.15271. Epub 2020 Apr 15.

Petter Brodin^{1

2}

¹ Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
² Unit of Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden.

No abstract available

Comment in

Physiological advantages of children against COVID-19.
Yavuz S, Kesici S, Bayrakci B. Yavuz S, et al. Acta Paediatr. 2020 Aug;109(8):1691. doi: 10.1111/apa.15410. Epub 2020 Jun 26. Acta Paediatr. 2020. PMID: 32533756 Free PMC article. No abstract available.

1. Korean Center for Disease and Control and Prevention. Press releases. https://www.cdc.go.kr/board/board.es?mid=a30402000000&bid=0030. Accessed March 22, 2020.
1. Simon AK, Hollander GA, McMichael A. Evolution of the immune system in humans from infancy to old age. Proc Biol Sic. 1821;2015(282):20143085.
1. Olin A, Henckel E, Chen Y, et al. Stereotypic immune system development in newborn children. Cell. 2018;174(5):1277-1292.e14.
1. Pou C, Nkulikiyimfura D, Henckel E, et al. The repertoire of maternal anti-viral antibodies in human newborns. Nat Med. 2019;25(4):591-596.
1. Nickbakhsh S, Mair C, Matthews L, et al. Virus-virus interactions impact the population dynamics of influenza and the common cold. Proc Natl Acad Sci USA. 2019;116(52):27142-27150.