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. 2019 Dec 20;7(24):4368-4371.
doi: 10.3889/oamjms.2019.837. eCollection 2019 Dec 30.

A Rare Colonic Metastasis Case from Hepatocellular Carcinoma

Binh Van Pham  1 , Huynh Huu Phan  1 , Lam Le Ngo  1 , Hang Thi Thuy Nguyen  1 , Ky Van Le  1 , Thien Chu Dinh  2 , Nguyen Duy Bac  3
Affiliations

A Rare Colonic Metastasis Case from Hepatocellular Carcinoma

Binh Van Pham et al. Open Access Maced J Med Sci. .

Abstract

Background: Hepatocellularcarcinoma (HCC) metastasis include intrahepatic and extrahepatic metastasis. Similar to intrahepatic metastasis, extrahepatic metastases are not unusual in cases with HCC. However, colonic metastasis is infrequent.

Case report: We describe a clinical case, he was diagnosed with HCC a year ago, treated with TACE (transarterialchemoembolisation), re-examined with abdominal pain and defecation disorder. The tests such as CT scan, colorectal endoscopy, fine needle aspiration (FNA) revealed secondary metastatic lesion of HCC in sigmoid colon. This is the first gastrointestinal (GI) tract metastatic we have encountered.

Conclusion: HCC metastases of the colon are rare, especially cases of hematogenous spread. The prognosis of these patients is often very critical. Indications for surgical removal of the lesion may be used if the general situation of patient is acceptable.

Keywords: GI metastasis; Hepatocelluar carcinoma; Sigmoid metastasis.

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Figures

Figure 1
Figure 1
CT scan result: A natural hypodense mass with 39 x 41 mm located in segment IV – VIII
Figure 2
Figure 2
The tumor is in submucosa, was composed of a typical polygonal cells that resemble HCC 2A) and vascular invasion 2B)
Figure 3
Figure 3
Immunohistochemicalstaiing, the tumor cells were positive for Hepar-1 3A) and Arginase-1 3B)
See this image and copyright information in PMC

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