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Editorial
. 2020 Mar 23;5(3):296-299.
doi: 10.1016/j.jacbts.2020.02.001. eCollection 2020 Mar.

Heart Failure With Preserved Ejection Fraction in Women: New Clues to Causes and Treatment

Matthias Barton  1   2 , Matthias R Meyer  1   3
Affiliations
Editorial

Heart Failure With Preserved Ejection Fraction in Women: New Clues to Causes and Treatment

Matthias Barton et al. JACC Basic Transl Sci. .
No abstract available

Keywords: HFpEF; HFrEF; PDE5; contractility; diastolic; estrogen; estrogen receptors; fibrosis; heart failure; hormone therapy; menopause; myocardial; phosphodiesterase-5; signaling; sildenafil; systolic.

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References

    1. Meyer M.R., Barton M. Estrogens and coronary artery disease: new clinical perspectives. Adv Pharmacol. 2016;77:307–360. - PubMed
    1. Menazza S., Murphy E. The expanding complexity of estrogen receptor signaling in the cardiovascular system. Circ Res. 2016;118:994–1007. - PMC - PubMed
    1. Horst B.G., Marletta M.A. Physiological activation and deactivation of soluble guanylate cyclase. Nitric Oxide. 2018;77:65–74. - PMC - PubMed
    1. Sasaki H., Nagayama T., Blanton R.M. PDE5 inhibitor efficacy is estrogen dependent in female heart disease. J Clin Invest. 2014;124:2464–2471. - PMC - PubMed
    1. Rodrigues Sabbatini A.R., Kararigas G. Menopause-related estrogen decrease and the pathogenesis of HFpEF: JACC Review Topic of the Week. J Am Coll Cardiol. 2020;75:1074–1082. - PubMed

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