Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb;114(2):222-231.
doi: 10.36660/abc.20180321.

A 10-Year Trend Analysis of Heart Failure in the Less Developed Brazil

[Article in English, Portuguese]
Affiliations

A 10-Year Trend Analysis of Heart Failure in the Less Developed Brazil

[Article in English, Portuguese]
Amanda D F Fernandes et al. Arq Bras Cardiol. 2020 Feb.

Abstract

Background: Data on heart failure (HF) epidemiology in less developed areas of Brazil are scarce.

Objective: Our aim was to determine the HF morbidity and mortality in Paraiba and Brazil and its 10-year trends.

Methods: A retrospective search was conducted from 2008 to 2017 using the DATASUS database and included patients ≥ 15 years old with a primary diagnosis of HF. Data on in-hospital and population morbidity and mortality were collected and stratified by year, gender and age. Pearson correlation and linear-by-linear association test for trends were calculated, with a level of significance of 5%.

Results: From 2008 to 2017, HF admissions decreased 62% (p = 0.004) in Paraiba and 34% (p = 0.004) in Brazil. The in-hospital mortality rate increased in Paraiba and Brazil [65.1% (p = 0.006) and 30.1% (p = 0.003), respectively], but the absolute in-hospital mortality had a significant decrease only in Paraiba [37.5% (p = 0.013)], which was maintained after age stratification, except for groups 15-19, 60-69 and > 80 years. It was observed an increase in the hospital stay [44% (p = 0.004) in Paraiba and 12.3% (p = 0.004) in Brazil]. From 2008 to 2015, mortality rate for HF in the population decreased 10.7% (p = 0.047) in Paraiba and 7.7% (p = 0.017) in Brazil.

Conclusions: Although HF mortality rate has been decreasing in Paraiba and Brazil, an increase in the in-hospital mortality rate and length of stay for HF has been observed. Hospital-based clinical studies should be performed to identify the causes for these trends of increase.

PubMed Disclaimer

Conflict of interest statement

Potential Conflict of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Trends in absolute number of hospitalizations from heart failure from 2008 to 2017 in Paraiba (A) and regions of Brazil (B).
Figure 2
Figure 2
Trends in population mortality rate (per 100,000 inhabitants) from heart failure in Paraiba (green) and Brazil (blue) from 2008 to 2015.
Figure 3
Figure 3
(A) Trend of the in-hospital mortality rate from heart failure in Paraiba (green) and Brazil (blue) from 2008 to 2017; (B) trend of the in-hospital absolute mortality from heart failure in Paraiba (green) and Brazil (blue) from 2008 to 2017.
Figure 4
Figure 4
(A) Absolute in-hospital deaths from heart failure in Paraiba per age range, from 2008 to 2017. (B) Absolute in-hospital deaths from heart failure in Brazil per age range, from 2008 to 2017.
Figure 5
Figure 5
(A) Trend of the in-hospital mortality rate from heart failure in Paraiba per year and age range, from 2008 to 2017. (B) Trend of the in-hospital mortality rate from heart failure in Brazil per year and age range, from 2008 to 2017.
Figure 6
Figure 6
Trends in the mean length of stay (days) from heart failure hospitalizations in Paraiba (green) and Brazil (blue) from 2008 to 2017

Comment in

References

    1. Lam CS, Donal E, Kraigher-Krainer E, Vasan RS. Epidemiology and clinical course of heart failure with preserved ejection fraction. Eur J Heart Fail. 2011;13(1):18–28. - PMC - PubMed
    1. Bocchi EA. Heart failure in South America. Curr Cardiol Rev. 2013;9(2):147–156. - PMC - PubMed
    1. Ambrosy AP, Fonarow GC, Butler J, Chioncel O, Greene SJ, Vaduganathan M, et al. The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries. J Am Coll Cardiol. 2014;63(12):1123–1133. - PubMed
    1. Chen J, Normand SL, Wang Y, Krumholz HM. National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008. JAMA. 2011;306(15):1669–1678. - PMC - PubMed
    1. Brazilian Institute of Geography and Statistics [2019 Apr 12]. Available from: https://cidades.ibge.gov.br/brasil/pb/panorama.