Coronavirus uses as binding site in humans angiotensin-converting enzyme 2 functional receptor that is involved in arterial blood pressure control and fibrotic response to damage and is a drug target in cardiovascular disease. Is this just a phylogenetic coincidence?
- PMID: 32216172
- PMCID: PMC7228413
- DOI: 10.1002/jmv.25774
Coronavirus uses as binding site in humans angiotensin-converting enzyme 2 functional receptor that is involved in arterial blood pressure control and fibrotic response to damage and is a drug target in cardiovascular disease. Is this just a phylogenetic coincidence?
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Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.J Med Virol. 2020 Jun;92(6):595-601. doi: 10.1002/jmv.25726. Epub 2020 Mar 11. J Med Virol. 2020. PMID: 32100877 Free PMC article.
