Corrigendum: Autoantibodies in renal diseases - clinical significance and recent developments in serological detection

Abstract

[This corrects the article on p. 221 in vol. 6, PMID: 26029207.].

Keywords: ANCA; anti-PLA2R; anti-PR3; anti-THSD7A; anti-dsDNA; anti-nucleosomes; autoantibodies; renal autoimmune diseases.

Figure 1

MPO-ANCA fluorescence pattern on the EUROIMMUN EUROPLUS™ Granulocyte Mosaic (IgG). (A) Examplary microscope slide with 10 reaction fields, each containing 6 biochips forming a mosaic. (B) In the EUROPLUS™ Granulocyte Mosaic, each biochip represents a different substrate: ethanol-fixed granulocytes [granulocytes (EOH)], formalin-fixed granulocytes [granulocytes (HCHO)], HEp-2 cells in combination with ethanol-fixed granulocytes [HEp-2 cells + granulocytes (EOH)] as well as PR3, MPO, and GBM microdots. The exemplary images illustrate the reactivity of a patient sample positive for anti-MPO and anti-GBM: Besides a P-ANCA pattern on ethanol-fixed granulocytes and a granular C-ANCA pattern on formalin-fixed granulocytes, MPO-ANCA is characterized by a positive fluorescence signal on MPO but not on PR3 microdots. In addition a positive fluorescence signal on GBM microdots is shown.