Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
- PMID: 32220278
- PMCID: PMC7138169
- DOI: 10.1016/S0140-6736(20)30691-7
Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
Comment on
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COVID-19: consider cytokine storm syndromes and immunosuppression.Lancet. 2020 Mar 28;395(10229):1033-1034. doi: 10.1016/S0140-6736(20)30628-0. Epub 2020 Mar 16. Lancet. 2020. PMID: 32192578 Free PMC article. No abstract available.
References
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- Boor PPC, de Ruiter PE, Asmawidjaja PS, Lubberts E, van der Laan LJW, Kwekkeboom J. JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa. Transl Res. 2017;188:67–79. - PubMed
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