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. 2020 Apr 16;181(2):223-227.
doi: 10.1016/j.cell.2020.03.035. Epub 2020 Mar 26.

A Genomic Perspective on the Origin and Emergence of SARS-CoV-2

Yong-Zhen Zhang  1 , Edward C Holmes  2
Affiliations

A Genomic Perspective on the Origin and Emergence of SARS-CoV-2

Yong-Zhen Zhang et al. Cell. .

Abstract

The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data reveal about the emergence SARS-CoV-2 and discuss the gaps in our understanding of its origins.

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Figures

Figure 1
Figure 1
The Huanan Seafood and Wildlife Market in Wuhan, China The photographs (credit: E.C.H.) were taken when both authors visited the market together in October 2014 and highlight some of the wide variety of wildlife on sale, providing a potent mechanism for zoonotic transmission. Importantly, although many of the early COVID-19 cases were linked to this market, its role in the initial emergence of SARS-CoV-2 remains uncertain.
See this image and copyright information in PMC

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