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Comment
. 2020 Jun:147:241-242.
doi: 10.1016/j.radonc.2020.03.001. Epub 2020 Mar 25.

Response to Ling et al. regarding "An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses"

Garry R Buettner  1 , Douglas R Spitz  1 , Charles L Limoli  2
Affiliations
Comment

Response to Ling et al. regarding "An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses"

Garry R Buettner et al. Radiother Oncol. 2020 Jun.
No abstract available

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Comment on

References

    1. Spitz DR, Buettner GR, Petronek MS, St-Aubin JJ, Flynn RT, Waldron TJ, et al. An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses. Radiother Oncol 2019;139:23–7. 10.1016/j.radonc.2019.03.028. PMID: 31010709. - DOI - PMC - PubMed
    1. Spitz DR, Buettner GR, Limoli CL. Response to letter regarding “An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses”. Radiother Oncol 2019;139:64–5. 10.1016/j.radonc.2019.07.009. PMID: 31427044. - DOI - PMC - PubMed
    1. Favaudon V, Caplier L, Monceau V Pouzoulet F, Sayarath M, Fouillade C, Poupon MF, et al. Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice. Sci Transl Med 2014;6: ra93. https://doi-org.proxy.lib.uiowa.edu/10.1126/scitranslmed.3008973. PMID: 25031268. - DOI - PubMed
    1. Wang HP, Qian SY, Schafer FQ, Domann FE, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase protects against the singlet oxygen-induced cell damage of photodynamic therapy. Free Radical Biol Med 2001;30:825–35. 10.1016/S0891-5849(01)00469-5. - DOI - PubMed