Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 30;14(3):e0008151.
doi: 10.1371/journal.pntd.0008151. eCollection 2020 Mar.

Is Sporothrix chilensis circulating outside Chile?

Carlos Alberto Tiburcio Valeriano  1 , Reginaldo Gonçalves de Lima-Neto  1   2 , Cícero Pinheiro Inácio  1 , Vanessa Brito de Souza Rabello  3 , Ertênia Paiva Oliveira  1 , Rosely Maria Zancopé-Oliveira  3 , Rodrigo Almeida-Paes  3 , Rejane Pereira Neves  1 , Manoel Marques Evangelista de Oliveira  4
Affiliations

Is Sporothrix chilensis circulating outside Chile?

Carlos Alberto Tiburcio Valeriano et al. PLoS Negl Trop Dis. .

Abstract

Sporothrix chilensis is a mild-pathogenical specie of Sporothrix pallida complex, until now, known as restrict to Chile. Herein, we describe the first clinical isolates identified as S. chilensis in Brazil, preserved in the URM Culture Collection, by polyphasic taxonomy, and their respective antifungal profile of this emergent fungus.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Evolutionary relationships of 18 taxa.
The evolutionary history was inferred using the Maximum Parsimony method. Tree #1 out of 107 most parsimonious trees (length = 53) is shown. The consistency index is 0.905660 (0.871795), the retention index is 0.962963 (0.962963), and the composite index is 0.872117 (0.839506) for all sites and parsimony-informative sites (in parentheses). The MP tree was obtained using the Close-Neighbor-Interchange algorithm with search level 2 in which the initial trees were obtained with the random addition of sequences (10 replicates). The tree is drawn to scale, with branch lengths calculated using the average pathway method and are in the units of the number of changes over the whole sequence. The codon positions included were 1st+2nd+3rd+Noncoding. All positions containing gaps and missing data were eliminated from the dataset (Complete Deletion option). There were a total of 175 positions in the final dataset, out of which 24 were parsimony informative. Phylogenetic analyses were conducted in MEGA4.
Fig 2
Fig 2. Macroscopic and microscopic morphologies of S. chilensis isolates.
(A) Colony of S. chilensis developed on PDA at 30°C, (B) Colony of S. chilensis developed on PDA at 37°C.
Fig 3
Fig 3
Microscopic morphologies of S. chilensis URM434 (A) URM435 (B), URM2439 (C), URM2865 (D).
See this image and copyright information in PMC

References

    1. Chakrabarti A, Bonifaz A, Gutierrez-Galhardo MC, Mochizuki T, Li S. Global epidemiology of sporotrichosis. Med Mycol. 2015. January;53(1):3–14. 10.1093/mmy/myu062 - DOI - PubMed
    1. Rodrigues AM, de Hoog GS, de Camargo ZP. Sporothrix Species Causing Outbreaks in Animals and Humans Driven by Animal-Animal Transmission. PLoS Pathog. 2016. July 14;12(7):e1005638 10.1371/journal.ppat.1005638 - DOI - PMC - PubMed
    1. Marimon R, Cano J, Gené J, Sutton DA, Kawasaki M, Guarro J. Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest. J Clin Microbiol. 2007;45(10): 3198–3206. 10.1128/JCM.00808-07 - DOI - PMC - PubMed
    1. Marimon R, Gené J, Cano J, Guarro J. Sporothrix luriei: rare fungus from clinical origin. Med Mycol. 2008;46(6):621–5. 10.1080/13693780801992837 - DOI - PubMed
    1. Madrid H, Cano J, Gené J, Bonifaz A, Toriello C, Guarro J. Sporothrix globosa, a pathogenic fungus with widespread geographical distribution. Rev Iberoam Micol. 2009;26(3):218–222. 10.1016/j.riam.2009.02.005 - DOI - PubMed

Publication types