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. 2012;82(1):209-224.
doi: 10.1007/s40011-011-0016-7. Epub 2012 Jan 18.

Anti-Viral Activity of Indian Plants

B N Dhawan  1
Affiliations

Anti-Viral Activity of Indian Plants

B N Dhawan. Proc Natl Acad Sci India Sect B Biol Sci. 2012.

Abstract

Plants continue to be a major source for new chemical entities to develop novel therapeutic agents. Large number of plants has been shown to be active in vitro against a variety of human pathogenic viruses or their near congeners. In several cases the active compounds have been isolated and characterized. Very few of them, however, have been investigated in detail in vivo or taken to the clinic. Pure compounds like andrographolide, curcumin and glycyrrhizic acid as well as extracts of Azadirachta indica have shown activity against several viruses and should be investigated further for their therapeutic potential. An analysis of available data from several hundred species indicates that antiviral activity is more likely to be found in plants belonging to certain families. It is necessary to screen more plants of these families which are available in India to obtain further leads.

Keywords: Antiviral activity; Herpes simplex; Human immunodeficiency virus; Indian plants; Interferon inducers; Respiratory viruses; Viral hepatitis.

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References

    1. Dhawan BN. Biodiversity as a source of new chemical entities. In: Tandon P, Sharma M, Swaroop R, editors. Biodiversity status and prospects. New Delhi: Narosa Publishing House; 2005. pp. 25–34.
    1. Mukherjee PK, Rai S, Kumar V, Hylands PJ, Hider RC. Plants of Indian origin in drug discovery. Expert Opin Drug Discov. 2007;2:637–653. - PubMed
    1. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. Screening of Indian plants for biological activity. Part I. Indian J Exp Biol. 1968;6:232–247. - PubMed
    1. Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN. Screening of Indian plants for biological activity. Part II. Indian J Exp Biol. 1969;7:250–262. - PubMed
    1. Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, Gupta B, Srimal RC. Screening of Indian plants for biological activity. Part III. Indian J Exp Biol. 1971;9:91–102. - PubMed

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