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Review
. 2020 Mar 15;16(10):1678-1685.
doi: 10.7150/ijbs.45053. eCollection 2020.

SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat

Jun Zheng  1   2
Affiliations
Review

SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat

Jun Zheng. Int J Biol Sci. .

Abstract

An ongoing outbreak of pneumonia caused by a novel coronavirus, currently designated as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was reported recently. However, as SARS-CoV-2 is an emerging virus, we know little about it. In this review, we summarize the key events occurred during the early stage of SARS-CoV-2 outbreak, the basic characteristics of the pathogen, the signs and symptoms of the infected patients as well as the possible transmission pathways of the virus. Furthermore, we also review the current knowledge on the origin and evolution of the SARS-CoV-2. We highlight bats as the potential natural reservoir and pangolins as the possible intermediate host of the virus, but their roles are waiting for further investigation. Finally, the advances in the development of chemotherapeutic options are also briefly summarized.

Keywords: COVID-19; Coronavirus; Novel coronavirus; SARS-CoV-2; pneumonia.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

Figures

Figure 1
Figure 1
Key events in the early stage of SARS-CoV-2 outbreak.
See this image and copyright information in PMC

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