Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Jun 9;22(6):746-747.
doi: 10.1093/neuonc/noaa082.

A Fyn romance: tumor cell Fyn kinase suppresses the immune microenvironment

Affiliations
Editorial

A Fyn romance: tumor cell Fyn kinase suppresses the immune microenvironment

Sachendra S Bais et al. Neuro Oncol. .
No abstract available

PubMed Disclaimer

Comment on

References

    1. Cloughesy TF, Mochizuki AY, Orpilla JR, et al. . Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma. Nat Med. 2019;25(3):477–486. - PMC - PubMed
    1. Chen Z, Feng X, Herting CJ, et al. . Cellular and molecular identity of tumor-associated macrophages in glioblastoma. Cancer Res. 2017;77(9):2266–2278. - PMC - PubMed
    1. Otvos B, Silver DJ, Mulkearns-Hubert EE, et al. . Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion. Stem Cells. 2016;34(8):2026–2039. - PMC - PubMed
    1. Daginakatte GC, Gutmann DH. Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth. Hum Mol Genet. 2007;16(9):1098–1112. - PubMed
    1. Gabrusiewicz K, Rodriguez B, Wei J, et al. . Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype. JCI Insight. 2016;1(2): pii: 85841. - PMC - PubMed

MeSH terms

Substances