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Case Reports
. 2020 Dec;64(6):814-816.
doi: 10.1111/1754-9485.13019. Epub 2020 Mar 30.

Metastatic melanoma presenting as intravenous tumour thrombus

Affiliations
Case Reports

Metastatic melanoma presenting as intravenous tumour thrombus

Jennifer Nguyen et al. J Med Imaging Radiat Oncol. 2020 Dec.

Abstract

Tumour thrombus is a complication that occurs when a malignancy invades into the vasculature, occluding its lumen. Here, we present a rare case of melanoma tumour thrombus of the great saphenous vein of the left thigh, which was diagnosed on 18 F-fluorodeoxyglucose positron emission tomography/computed tomography and ultrasound-guided biopsy, and responded well to immunotherapy with pembrolizumab.

Keywords: F-18 FDG PET/CT; immunotherapy; melanoma; metastasis; tumour thrombus.

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References

    1. Quencer KB, Friedman T, Sheth R, Oklu R. Tumour thrombus: incidence, imaging, prognosis and treatment. Cardiovasc Diagn Ther 2017; 7 (Suppl 3): S165-77.
    1. Vauthey JN, Winter MW, Blumgart LH. Solitary metastasis from cutaneous melanoma to the liver: resection by extended left hepatectomy (trisegmentectomy) with clearance of tumour from the portal vein. HPB Surg 1994; 8: 53-6.
    1. Mizushima T, Tanioka H, Emori Y et al. Metastatic pancreatic malignant melanoma: tumour thrombus formed in portal venous system 15 years after initial surgery. Pancreas 2003; 27: 201-3.
    1. Saint-Cyr I, Boisseau-Garsaud AM, Pont F, Cales-Quist D, Helenon R, Chinyavong T. Intravascular metastatic melanoma of the vena saphena magna. Int J Dermatol 2004; 43: 590-2.
    1. Klatte T, Rao JY, Ribas A, Pantuck AJ. Metastatic melanoma to the kidney presenting with renal vein tumour thrombus. Urology 2007; 69: 982.

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