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Review
. 2020 Mar 27;69(Suppl 1):S29-S34.
doi: 10.33549/physiolres.934398.

Biomarkers of Bronchial Asthma

P Kunc  1 , J Fabry, M Lucanska, R Pecova
Affiliations
Review

Biomarkers of Bronchial Asthma

P Kunc et al. Physiol Res. .

Abstract

Asthma is a complex disease with a variable course. Efforts to identify biomarkers to predict asthma severity, the course of disease and response to treatment have not been very successful so far. Biomarker research has expanded greatly with the advancement of molecular research techniques. An ideal biomarker should be suitable to identify the disease as well the specific endotype/phenotype, useful in the monitoring of the disease and to determine the prognosis, easily to obtain with minimum discomfort or risk to the patient. An ideal biomarker should be suitable to identify the disease as well the specific endotype/phenotype, useful in the monitoring of the disease and to determine the prognosis, easily to obtain with minimum discomfort or risk to the patient - exhaled breath analysis, blood cells and serum biomarkers, sputum cells and mediators and urine metabolites could be potential biomarkers of asthma bronchiale. Unfortunately, at the moment, an ideal biomarker doesn't exist and the overlap between the biomarkers is a reality. Using panels of biomarkers could improve probably the identification of asthma endotypes in the era of precision medicine.

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Conflict of interest statement

Conflict of Interest

There is no conflict of interest.

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