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Review
. 2020 Nov;176(9):661-669.
doi: 10.1016/j.neurol.2019.12.009. Epub 2020 Mar 27.

Imaging of the aging brain and development of MRI signal abnormalities

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Review

Imaging of the aging brain and development of MRI signal abnormalities

H Chabriat et al. Rev Neurol (Paris). 2020 Nov.

Abstract

Major changes occur at the cerebral level with aging. Cerebral atrophy develops progressively. Multiple lesions related to small-vessel diseases are detected in association with cerebral atrophy including white-matter hyperintensities, lacunes, microbleeds, dilated perivascular spaces and cerebral, including cortex, atrophy. The clinical impact and predictive value of these Imaging makers were examined.

Keywords: Aging; Atrophy; Lacunes; Microbleeds; Perivascular spaces; White-matter.

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