Imaging of the aging brain and development of MRI signal abnormalities
- PMID: 32229042
- DOI: 10.1016/j.neurol.2019.12.009
Imaging of the aging brain and development of MRI signal abnormalities
Abstract
Major changes occur at the cerebral level with aging. Cerebral atrophy develops progressively. Multiple lesions related to small-vessel diseases are detected in association with cerebral atrophy including white-matter hyperintensities, lacunes, microbleeds, dilated perivascular spaces and cerebral, including cortex, atrophy. The clinical impact and predictive value of these Imaging makers were examined.
Keywords: Aging; Atrophy; Lacunes; Microbleeds; Perivascular spaces; White-matter.
Copyright © 2020 Elsevier Masson SAS. All rights reserved.
Similar articles
-
Intracranial Arterial Dolichoectasia and Stenosis: Risk Factors and Relation to Cerebral Small Vessel Disease.Stroke. 2018 May;49(5):1135-1140. doi: 10.1161/STROKEAHA.117.020130. Epub 2018 Mar 26. Stroke. 2018. PMID: 29581240
-
Classification of white matter lesions and characteristics of small vessel disease markers.Eur Radiol. 2023 Feb;33(2):1143-1151. doi: 10.1007/s00330-022-09070-1. Epub 2022 Aug 18. Eur Radiol. 2023. PMID: 35980432
-
Dilated perivascular spaces in small-vessel disease: a study in CADASIL.Cerebrovasc Dis. 2014;37(3):155-63. doi: 10.1159/000356982. Epub 2014 Feb 5. Cerebrovasc Dis. 2014. PMID: 24503815
-
Effect of Antihypertensive Medication on Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis.Stroke. 2018 Jun;49(6):1531-1533. doi: 10.1161/STROKEAHA.118.021160. Epub 2018 May 8. Stroke. 2018. PMID: 29739911
-
Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease.J Cereb Blood Flow Metab. 2016 Aug;36(8):1319-37. doi: 10.1177/0271678X16647396. Epub 2016 May 11. J Cereb Blood Flow Metab. 2016. PMID: 27170700 Free PMC article. Review.
Cited by
-
Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease.Front Neurol. 2025 Feb 11;16:1462636. doi: 10.3389/fneur.2025.1462636. eCollection 2025. Front Neurol. 2025. PMID: 40007740 Free PMC article.
-
The Open-Access European Prevention of Alzheimer's Dementia (EPAD) MRI dataset and processing workflow.Neuroimage Clin. 2022;35:103106. doi: 10.1016/j.nicl.2022.103106. Epub 2022 Jul 7. Neuroimage Clin. 2022. PMID: 35839659 Free PMC article.
-
Prevalence and Consequences of Cerebral Small Vessel Diseases: A Cross-Sectional Study Based on Community People Plotted Against 5-Year Age Strata.Neuropsychiatr Dis Treat. 2022 Mar 3;18:499-512. doi: 10.2147/NDT.S352651. eCollection 2022. Neuropsychiatr Dis Treat. 2022. PMID: 35264852 Free PMC article.
-
Global research trends on the links between glymphatic system and cognition: A bibliometric analysis (2009-2023).Medicine (Baltimore). 2025 Jun 27;104(26):e42166. doi: 10.1097/MD.0000000000042166. Medicine (Baltimore). 2025. PMID: 40587680 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical