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Review
. 2020 Mar 30;25(7):1591.
doi: 10.3390/molecules25071591.

The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?

Sarai Quirante-Moya  1 , Paula García-Ibañez  2   3 , Francisco Quirante-Moya  2 , Débora Villaño  4 , Diego A Moreno  3
Affiliations
Review

The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?

Sarai Quirante-Moya et al. Molecules. .

Abstract

Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed on the lack of established and standardized protocols. The different concentration of bioactive compounds used, time of intervention or sample size, and the lack of blinding are some factors that may influence the studies' outcomes. This review aims to analyze the critical points of the studies performed with Brassica-related biomolecules and propose some bases for future trials in order to avoid biases.

Keywords: Brassica; clinical trials; glucosinolates.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
General scheme of the glucosinolates (GSLs) and common hydrolysis products. ESP: Epithiospecifer proteins.
See this image and copyright information in PMC

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