Weighing up effects of extra chromosomes

Affiliations

Comment

Sarah Seton-Rogers. Nat Rev Cancer. 2020 May.

. 2020 May;20(5):259.

doi: 10.1038/s41568-020-0257-y.

No abstract available

Comment on

Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer.
Vasudevan A, Baruah PS, Smith JC, Wang Z, Sayles NM, Andrews P, Kendall J, Leu J, Chunduri NK, Levy D, Wigler M, Storchová Z, Sheltzer JM. Vasudevan A, et al. Dev Cell. 2020 Feb 24;52(4):413-428.e6. doi: 10.1016/j.devcel.2020.01.034. Dev Cell. 2020. PMID: 32097652 Free PMC article.
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López S, Lim EL, Horswell S, Haase K, Huebner A, Dietzen M, Mourikis TP, Watkins TBK, Rowan A, Dewhurst SM, Birkbak NJ, Wilson GA, Van Loo P, Jamal-Hanjani M; TRACERx Consortium; Swanton C, McGranahan N. López S, et al. Nat Genet. 2020 Mar;52(3):283-293. doi: 10.1038/s41588-020-0584-7. Epub 2020 Mar 5. Nat Genet. 2020. PMID: 32139907 Free PMC article.

1. López, S. et al. Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution. Nat. Genet. 52, 283–293 (2020) - PubMed - DOI
1. Vasudevan, A. et al. Single-chromosomal gains can function as metastasis suppressors and promoters in colon cancer. Dev. Cell 52, 413–428 (2020) - PubMed - DOI