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Review
. 2020 Jun;39(3):246-250.
doi: 10.1080/15513815.2020.1747120. Epub 2020 Apr 2.

Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review

Mojgan Karimi-Zarchi  1   2 , Hossein Neamatzadeh  3   4 , Seyed Alireza Dastgheib  5 , Hajar Abbasi  6 , Seyed Reza Mirjalili  4   7 , Athena Behforouz  6 , Farzad Ferdosian  7   8 , Reza Bahrami  9
Affiliations
Review

Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review

Mojgan Karimi-Zarchi et al. Fetal Pediatr Pathol. 2020 Jun.

Abstract

Background: Since early December 2019, the Coronavirus Disease 19 (COVID-19) infection has been prevalent in China and eventually spread to other countries. There are a few published cases of COVID-19 occurring during pregnancy and due the possibility of mother-fetal vertical transmission, there is a concern that the fetuses may be at risk of congenital COVID-19. Methods: We reviewed the risk of vertical transmission of COVID-19 to the fetus of infected mothers by using data of published articles or official websites up to March 4, 2020. Results: A total of 31 infected pregnant mothers with COVID-19 were reported. No COVID-19 infection was detected in their neonates or placentas. Two mothers died from COVID-19-related respiratory complications after delivery. Conclusions: Currently, based on limited data, there is no evidence for intrauterine transmission of COVID-19 from infected pregnant women to their fetuses. Mothers may be at increased risk for more severe respiratory complications.

Keywords: COVID-19; Corona Virus; neonate; placenta; pregnant mothers; vertical transmission.

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References

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