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. 2020 Apr 17;22(8):3099-3103.
doi: 10.1021/acs.orglett.0c00856. Epub 2020 Apr 3.

Clickable Bambusurils to Access Multivalent Architectures

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Clickable Bambusurils to Access Multivalent Architectures

Marine Lafosse et al. Org Lett. .

Abstract

Propargylated bambus[4,6]urils were prepared by an efficient one-step condensation of dipropargylglycoluril with formaldehyde under microwave irradiation. Their functionalization by click chemistry (CuAAC) afforded new multivalent architectures decorated with 8 or 12 ligands. Grafting of glycosides provided water-soluble glycobambus[4,6]uril platforms with glucosyl12BU[6] showing good affinity toward iodide anion in aqueous medium.

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