Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep 15;202(6):795-802.
doi: 10.1164/rccm.201912-2332WS.

E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report

Laura E Crotty Alexander  1   2 , Lorraine B Ware  3   4 , Carolyn S Calfee  5 , Sean J Callahan  6   7 , Thomas Eissenberg  8   9 , Carol Farver  10 , Maciej L Goniewicz  11 , Ilona Jaspers  12 , Farrah Kheradmand  13   14 , Talmadge E King, Jr  5 , Nuala J Meyer  15 , Vladimir B Mikheev  16 , Peter G Shields  17 , Alan Shihadeh  18 , Robert Strongin  19 , Robert Tarran  20
Affiliations

E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report

Laura E Crotty Alexander et al. Am J Respir Crit Care Med. .

Abstract

The NHLBI convened a working group on October 23, 2019, to identify the most relevant and urgent research priorities and prevailing challenges in e-cigarette or vaping product use-associated lung injury (EVALI). Experts across multiple disciplines discussed the complexities of the EVALI outbreak, identified research priorities, and recommended strategies to address most effectively its causal factors and improve diagnosis, treatment, and prevention of this disease. Many research priorities were identified, including the need to create national and international registries of patients with EVALI, to track accurately those affected and assess outcomes. The group concluded that biospecimens from subjects with EVALI are urgently needed to help define EVALI pathogenesis and that vaping has disease risks that are disparate from smoking, with the occurrence of EVALI highlighting the importance of broadening e-cigarette research beyond comparators to smoking-related diseases.

Keywords: EVALI; THC; e-cigarette; research; vaping.

PubMed Disclaimer

References

    1. Viswam D, Trotter S, Burge PS, Walters GI. Respiratory failure caused by lipoid pneumonia from vaping e-cigarettes. BMJ Case Rep. 2018;2018:bcr-2018-224350. - PMC - PubMed
    1. Sommerfeld CG, Weiner DJ, Nowalk A, Larkin A. Hypersensitivity pneumonitis and acute respiratory distress syndrome from E-cigarette use. Pediatrics. 2018;141:e20163927. - PubMed
    1. Agustin M, Yamamoto M, Cabrera F, Eusebio R. Diffuse alveolar hemorrhage induced by vaping. Case Rep Pulmonol. 2018;2018:9724530. - PMC - PubMed
    1. Thota D, Latham E. Case report of electronic cigarettes possibly associated with eosinophilic pneumonitis in a previously healthy active-duty sailor. J Emerg Med. 2014;47:15–17. - PubMed
    1. Arter ZL, Wiggins A, Hudspath C, Kisling A, Hostler DC, Hostler JM. Acute eosinophilic pneumonia following electronic cigarette use. Respir Med Case Rep. 2019;27:100825. - PMC - PubMed

Publication types