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. 2020 Apr 2;181(1):208-208.e1.
doi: 10.1016/j.cell.2020.02.032.

Snapshot: Trial Types in Precision Medicine

Dane Dickson  1 , Jennifer Johnson  2 , Raymond Bergan  3 , Rebecca Owens  4 , Vivek Subbiah  5 , Razelle Kurzrock  6
Affiliations
Free article

Snapshot: Trial Types in Precision Medicine

Dane Dickson et al. Cell. .
Free article

Abstract

Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.

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