Comment
doi: 10.1016/j.stem.2020.03.011.
Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures
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- PMID: 32243802
- DOI: 10.1016/j.stem.2020.03.011
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Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures
Cell Stem Cell.
.
Free article
Abstract
Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.
Copyright © 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of Interests A.H.B is a co-founder of two start-up companies, Rumi Scientific Inc. and OvaNova Laboratories, LLC, and serves on their scientific advisory boards.
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Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids.Nature. 2020 Jun;582(7812):405-409. doi: 10.1038/s41586-020-2024-3. Epub 2020 Feb 19. Nature. 2020. PMID: 32076263
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