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Comment
. 2020 Apr 2;26(4):467-468.
doi: 10.1016/j.stem.2020.03.011.

Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Edwin A Rosado-Olivieri  1 , Ali H Brivanlou  2
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Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures

Edwin A Rosado-Olivieri et al. Cell Stem Cell. .
Free article

Abstract

Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.

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Conflict of interest statement

Declaration of Interests A.H.B is a co-founder of two start-up companies, Rumi Scientific Inc. and OvaNova Laboratories, LLC, and serves on their scientific advisory boards.

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