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. 2020 Apr 2;78(1):5-8.
doi: 10.1016/j.molcel.2020.03.015.

The Interlocking Lives of LARP7: Fine-Tuning Transcription, RNA Modification, and Splicing through Multiple Non-coding RNAs

Mikko J Frilander  1 , Matjaž Barborič  2
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The Interlocking Lives of LARP7: Fine-Tuning Transcription, RNA Modification, and Splicing through Multiple Non-coding RNAs

Mikko J Frilander et al. Mol Cell. .
Free article

Abstract

Elegant studies by Hasler et al. (2020) and Wang et al. (2020) uncover a novel role of LARP7 in facilitating the 2'-O-methylation of the spliceosomal U6 snRNA, which is functionally required for fidelity of pre-mRNA splicing and development of male germ cells.

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