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Comment
. 2020 May;10(5):638.
doi: 10.1158/2159-8290.CD-RW2020-049. Epub 2020 Apr 3.

Somatic Copy-Number Alterations Contribute to Brain Metastasis

No authors listed
Comment

Somatic Copy-Number Alterations Contribute to Brain Metastasis

No authors listed. Cancer Discov. 2020 May.

Abstract

In lung cancer, brain metastasis was associated with somatic amplification of MYC, YAP1, or MMP13.

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  • Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma.
    Shih DJH, Nayyar N, Bihun I, Dagogo-Jack I, Gill CM, Aquilanti E, Bertalan M, Kaplan A, D'Andrea MR, Chukwueke U, Ippen FM, Alvarez-Breckenridge C, Camarda ND, Lastrapes M, McCabe D, Kuter B, Kaufman B, Strickland MR, Martinez-Gutierrez JC, Nagabhushan D, De Sauvage M, White MD, Castro BA, Hoang K, Kaneb A, Batchelor ED, Paek SH, Park SH, Martinez-Lage M, Berghoff AS, Merrill P, Gerstner ER, Batchelor TT, Frosch MP, Frazier RP, Borger DR, Iafrate AJ, Johnson BE, Santagata S, Preusser M, Cahill DP, Carter SL, Brastianos PK. Shih DJH, et al. Nat Genet. 2020 Apr;52(4):371-377. doi: 10.1038/s41588-020-0592-7. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203465 Free PMC article.

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