Tuberculosis and ovarian malignancy: Sometimes mimics, sometimes coexists
- PMID: 32246574
- DOI: 10.1111/jog.14223
Tuberculosis and ovarian malignancy: Sometimes mimics, sometimes coexists
Abstract
Tuberculosis is a disease prevalent all over the world with India contributing to a larger share. Pulmonary tuberculosis presents with generalized symptoms of malaise, low grade fever and cough. On the other hand, genital tuberculosis presents with a variety of symptoms in each age group and is often underdiagnosed and missed. In an unmarried female, the usual presentations are menstrual complaints or presence of a solid cystic mass and ascites. In reproductive age group, patients may present with primary or secondary infertility or rarely with tubo-ovarian masses with peritoneal deposits, omental thickening and lymph node enlargement, hence mimicking ovarian carcinoma. In postmenopausal females, it can present as postmenopausal bleeding, leucorrhea or pyometra giving suspicion of endometrial carcinoma. We hereby report two cases operated with provisional diagnosis of ovarian malignancy but final histopathology ruled out malignancy in first and confirmed coexistence of malignancy and tuberculosis in another.
Keywords: dysgerminoma; genital tuberculosis; ovarian neoplasm; postmenopausal bleeding; tubo-ovarian mass.
© 2020 Japan Society of Obstetrics and Gynecology.
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References
-
- India TB Report 2018. New Delhi: Central TB Division, 2018; 9.
-
- Malhotra N. Jeffcoate's Principles of Gynaecology, 8th edn. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd, 2014; 330-331.
-
- Hasanzadeh M, Naderi HR, Hoshyar AH, Shabane S, Shahidsales S. Female genital tract tuberculosis presenting as ovarian cancer. J Res Med Sci 2014; 19: 184-189.
-
- Agarwala A, Dhua A, Shamim S, Roy PP. Ovarian tubercular abscess mimicking ovarian carcinoma: A rare case report. J Assoc Chest Phys 2015; 3: 14-16.
-
- Ankrah AO, van der Werf TS, de Vries EF, Dierckx RA, Sathekge MM, Glaudemans AW. PET/CT imaging of Mycobacterium tuberculosis infection. Clin Transl Imaging 2016; 4: 131-144.
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