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Editorial
. 2020 Apr;287(7):1260-1261.
doi: 10.1111/febs.15296.

Enzyme promiscuity and evolution in light of cellular metabolism

Dan S Tawfik  1
Affiliations
Free article
Editorial

Enzyme promiscuity and evolution in light of cellular metabolism

Dan S Tawfik. FEBS J. 2020 Apr.
Free article

Abstract

This Special Issue is composed of 10 reviews that delve into the intricacies behind enzyme promiscuity and evolution, an area that is of increasing interest in the biological research community. In particular, the reviews in this Special Issue explore enzyme promiscuity and evolution in the context of cellular metabolism, as discussed in this introductory Editorial. It is our hope that you enjoy these fascinating and informative reviews and we wish to thank the authors for their compelling contributions to The FEBS Journal. doi: 10.1111/febs.12650.

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References

    1. Copley S (2020) Evolution of new enzymes by gene duplication and divergence. FEBS J 287, 1262-1283.
    1. Adams ST Jr & Miller SC (2019) Enzymatic promiscuity and the evolution of bioluminescence. FEBS J 287, 1369-1380.
    1. Glasner ME, Truong DP & Morse BC (2019) How enzyme promiscuity and horizontal gene transfer contribute to metabolic innovation. FEBS J 287, 1323-1342.
    1. Tawfik D & Gruic-Sovulj I (2019) How evolution shapes enzyme selectivity - lessons from aminoacyl-tRNA synthetases and other amino acid utilizing enzymes. FEBS J 287, 1284-1305.
    1. Atkins WM (2019) Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters. FEBS J 287, 1306-1322.

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