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Review
. 2020 May 8;126(10):1443-1455.
doi: 10.1161/CIRCRESAHA.120.317055. Epub 2020 Apr 7.

COVID-19 and the Heart

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Free article
Review

COVID-19 and the Heart

Akbarshakh Akhmerov et al. Circ Res. .
Free article

Abstract

Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.

Keywords: biomarkers; cardiovascular diseases; coronavirus; inflammation; myocarditis.

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