Transcription factors regulate adipocyte differentiation in beef cattle
- PMID: 32253788
- DOI: 10.1111/age.12931
Transcription factors regulate adipocyte differentiation in beef cattle
Abstract
Intramuscular fat (IMF) content is a critical factor affecting meat flavor, juiciness, tenderness, and color. Therefore, the improvement of IMF content is one of the hotspots of animal science research. Fat deposition is the result of a combination of increased number of fat cells and cellular hypertrophy. In addition, transcription factors can influence the number of adipocytes and regulate lipid metabolism. The progress of the transcription factors regulating adipocyte differentiation in beef cattle, including IMF cell sources, and promoting or inhibiting adipogenic differentiation of transcription factors is reviewed in this paper.
Keywords: adipocyte differentiation; beef cattle; intramuscular fat; molecular mechanism; transcription factors.
© 2020 Stichting International Foundation for Animal Genetics.
References
-
- Adoligbe C., Huangfu Y.F., Zan L.S. & Wang H. (2015) C/EBPalpha gene as a genetic marker for beef quality improvement. Genetics and Molecular Research 14, 9370-83.
-
- Banerjee S.S., Feinberg M.W., Watanabe M., Gray S., Haspel R.L., Denkinger D.J., Kawahara R., Hauner H. & Jain M.K. (2003) The Kruppel-like factor KLF2 inhibits peroxisome proliferator-activated receptor-gamma expression and adipogenesis. Journal of Biological Chemistry 278, 2581-4.
-
- Berry R., Jeffery E. & Rodeheffer M.S. (2014) Weighing in on adipocyte precursors. Cell Metabolism 19, 8-20.
-
- Bong J.J., Cho K.K. & Baik M. (2009) Comparison of gene expression profiling between bovine subcutaneous and intramuscular adipose tissues by serial analysis of gene expression. Cell Biology International 34, 125-33.
-
- Burgos S.A., Kim J.J., Dai M. & Cant J.P. (2013) Energy depletion of bovine mammary epithelial cells activates AMPK and suppresses protein synthesis through inhibition of mTORC1 signaling. Hormone and Metabolic Research 45, 183-9.
Publication types
MeSH terms
Substances
Grants and funding
- 31672403/National Natural Science Foundation of China
- 03010360052/Science and Technology Innovation Team of Ningxia Hui Autonomous Region
- 194200510022/The Thousand Talents Plan of Henan Province-Central Plains Science And Technology Innovation Leading Talents Project
- 2019BEB04006/Ningxia Hui Autonomous Region Key Research and Development Project
LinkOut - more resources
Full Text Sources
Other Literature Sources
