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. 2020 Nov 19;71(16):2227-2229.
doi: 10.1093/cid/ciaa394.

Towards Optimization of Hydroxychloroquine Dosing in Intensive Care Unit COVID-19 Patients

Sophie Perinel  1   2 , Manon Launay  3 , Élisabeth Botelho-Nevers  4 , Éric Diconne  1 , Aurore Louf-Durier  1 , Raphaël Lachand  1 , Martin Murgier  1 , Dominique Page  1 , Régine Vermesch  1 , Guillaume Thierry  1 , Xavier Delavenne  2   3
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Towards Optimization of Hydroxychloroquine Dosing in Intensive Care Unit COVID-19 Patients

Sophie Perinel et al. Clin Infect Dis. .

Abstract

Hydroxychloroquine (HCQ) appears to be a promising treatment for COVID-19. However, all ongoing clinical trials with HCQ use different dosing regimens, resulting in various concentrations. Pharmacokinetic studies are therefore needed to define the optimal dosing regimen.

Keywords: COVID-19; SARS-Cov2; hydroxychloroquine; intensive care; pharmacokinetic.

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