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Editorial
. 2020 Apr 17;134(7):747-750.
doi: 10.1042/CS20200363.

ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

Rhian M Touyz  1 , Hongliang Li  2 , Christian Delles  1
Affiliations
Editorial

ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

Rhian M Touyz et al. Clin Sci (Lond). .

Abstract

Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.

Keywords: ACE2 receptor; Angiotensin; COVID-19; cardiovascular; coronavirus; hypertension.

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