Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Sep;51(9):1134-41.
doi: 10.1136/jnnp.51.9.1134.

Physiological characterisation of the "warm up" effect of activity in patients with myotonic dystrophy

R G Cooper  1 , M J Stokes, R H Edwards
Affiliations

Physiological characterisation of the "warm up" effect of activity in patients with myotonic dystrophy

R G Cooper et al. J Neurol Neurosurg Psychiatry. 1988 Sep.

Abstract

Contractile properties of adductor pollicis muscle were examined over a range of stimulation frequencies in patients with myotonic dystrophy and normal subjects. In patients, fresh muscle demonstrated impaired relaxation, weakness at all frequencies and selective loss of force and excitation at high frequencies. During stimulated "fatiguing" activity, patients showed improvements in force and relaxation which appeared to result from normalisation of membrane excitation. Normal twitch potentiation also occurred during activity suggesting intact excitation-contraction coupling. These electrophysiological findings help to characterise and explain the "warm up" effect described by patients.

PubMed Disclaimer

References

    1. Am J Physiol. 1968 Feb;214(2):330-6 - PubMed
    1. Brain. 1959 Mar;82(1):81-91 - PubMed
    1. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):132-9 - PubMed
    1. J Physiol. 1972 Jun;223(2):507-23 - PubMed
    1. J Physiol. 1974 Jul;240(2):505-15 - PubMed

Publication types

LinkOut - more resources