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. 2020 Mar 10:2020:5301568.
doi: 10.1155/2020/5301568. eCollection 2020.

Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta-Analysis

Yonghui Hou  1   2 , Ying Liu  2 , Minying Li  1 , Baile Ning  1 , Zehuai Wen  1   3 , Wenbin Fu  1
Affiliations

Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta-Analysis

Yonghui Hou et al. Evid Based Complement Alternat Med. .

Abstract

Objectives: To systematically assess the efficacy of acupuncture combined with rehabilitation on unilateral neglect after stroke.

Methods: The Cochrane Library, PubMed, Excerpt Medical Database (EMBASE), China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (CBM), and Wan Fang databases were searched online for randomised controlled trials (RCTs) of acupuncture and its effects on unilateral neglect after stroke from their inception to September 2019. RCTs on acupuncture combined with rehabilitation in the experimental group for unilateral neglect compared with rehabilitation alone or rehabilitation plus sham acupuncture in the control group were included. Two authors separately screened the literature, extracted the data, and evaluated the quality of the included studies. Review Manager 5.3 software was used for the data analysis.

Results: A total of 542 patients from nine RCTs were included. The meta-analysis showed that the experimental groups could significantly improve Fugl-Meyer Assessment (FMA) (MD = 11.54, 95% CI [9.54, 13.54], P < 0.00001) and the ability of daily living (SMD = 1.35, 95% CI [0.64, 2.07], P < 0.00001) and the ability of daily living (SMD = 1.35, 95% CI [0.64, 2.07], P < 0.00001) when compared with the control groups. However, there was no significant difference in the drop of Catherine Bergego Scale (CBS) and Behavioural Inattention Test-conventional (BIT-C) between the two groups.

Conclusions: Acupuncture combined with rehabilitation was more effective in improving the motor function and the ability of daily living. Because of the limitations regarding the quantity and quality of the studies in this meta-analysis, high-quality and well-designed RCTs are necessary to validate the above conclusions.

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Conflict of interest statement

The authors declare that they have no conflicts of interest in the research.

Figures

Figure 1
Figure 1
Flow chart for study selection.
Figure 2
Figure 2
(a) Risk of bias summary. (b) Risk of bias graph.
Figure 3
Figure 3
Forest plot of FMA.
Figure 4
Figure 4
Forest plot of activity of daily living.
Figure 5
Figure 5
Forest plot of CBS.
See this image and copyright information in PMC

References

    1. Wu P., Mills E., Moher D., Seely D. Acupuncture in poststroke rehabilitation. Stroke. 2010;41(4):171–179. doi: 10.1161/strokeaha.109.573576. - DOI - PubMed
    1. Nijboer T., Port I. v. d., Schepers V., Post M., Meily A. V. Predicting functional outcome after stroke: the influence of neglect on basic activities in daily living. Frontiers in Human Neuroscience. 2013;7(5):p. 182. doi: 10.3389/fnhum.2013.00182. - DOI - PMC - PubMed
    1. Muri R. M., Cazzoli D., Nef T., Mosimann P., Hopfner S., Nyffeler T. Noninvasive brain stimulation in neglect rehabilitation: an update. Frontiers in Human Neuroscience. 2013;7(1):p. 248. doi: 10.3389/fnhum.2013.00248. - DOI - PMC - PubMed
    1. Jehkonen M., Laihosalo M., Kettunen J. E. Impact of neglect on functional outcome after stroke: a review of methodological issues and recent research findings. Restorative Neurology and Neuroscience. 2006;24(4–6):209–215. - PubMed
    1. Kortte K., Hillis A. E. Recent advances in the understanding of neglect and anosognosia following right hemisphere stroke. Current Neurology and Neuroscience Reports. 2009;9(6):459–465. doi: 10.1007/s11910-009-0068-8. - DOI - PMC - PubMed

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