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Review
. 2020 Apr 4;15(3):110-114.
doi: 10.1002/cld.894. eCollection 2020 Mar.

The Pathophysiology of Cholestasis and Its Relevance to Clinical Practice

Fernanda Q Onofrio  1   2 , Gideon M Hirschfield  1   2
Affiliations
Review

The Pathophysiology of Cholestasis and Its Relevance to Clinical Practice

Fernanda Q Onofrio et al. Clin Liver Dis (Hoboken). .

Abstract

http://aasldpubs.onlinelibrary.wiley.com/hub/journal/10.1002/(ISSN)2046-2484/video/15-3-reading-hirschfield a video presentation of this article http://aasldpubs.onlinelibrary.wiley.com/hub/journal/10.1002/(ISSN)2046-2484/video/15-3-interview-hirschfield an interview with the author https://www.wileyhealthlearning.com/Activity/7058609/disclaimerspopup.aspx questions and earn CME.

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Figures

Figure 1
Figure 1
Mechanistic themes in cholestatic liver disease.
See this image and copyright information in PMC

References

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    1. Nguyen KD, Sundaram V, Ayoub WS. Atypical causes of cholestasis. World J Gastroenterol 2014;20:9418‐9426. - PMC - PubMed
    1. Hirschfield GM, Heathcote J, Gershwin ME. Pathogenesis of cholestatic liver disease and therapeutic approaches. Gastroenterology 2010;139:1481‐1496. - PubMed
    1. European Association for the Study of the Liver . EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. J Hepatol 2017;67:145‐172. - PubMed
    1. Beuers U, Trauner M, Jansen P, et al. New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond. J Hepatol 2015;62(suppl 1):S25‐S37. - PubMed