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Case Reports
. 2020 Mar 23:2020:6935834.
doi: 10.1155/2020/6935834. eCollection 2020.

Mesenteric Lymph Node Recurrence of a Primary Colorectal Leiomyosarcoma

Amélie Beauchamp  1   2 , Roy Hajjar  1   2 , Sharmila Khullar  3 , Mathieu Latour  3 , Frank Schwenter  1   2 , Herawaty Sebajang  1   2
Affiliations
Case Reports

Mesenteric Lymph Node Recurrence of a Primary Colorectal Leiomyosarcoma

Amélie Beauchamp et al. Case Rep Surg. .

Abstract

Primary colorectal leiomyosarcoma is an excessively rare entity. It is associated with an aggressive behavior and typically favor hematogenous spread. The current standard of care is surgical resection. A 49-year-old patient presented with a 2-month history of fever. A PET-scan revealed a hypermetabolic mass in the transverse colon, and colonoscopy confirmed a tumor. A right hemicolectomy was performed. Histopathological diagnosis was of a leiomyosarcoma. Fourteen months after the surgery, a follow-up abdominal scan revealed a 2 cm mesenteric lymph node that was hypermetabolic on PET-scan. The mesenteric lymph node was resected and histopathology confirmed a leiomyosarcoma metastasis. This case opens the controversy on the management of rare lymph node recurrences in colorectal leiomyosarcoma.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Transverse colon mass seen on abdominoplevic scan and PET-scan (FDG).
Figure 2
Figure 2
Transverse colon mass during colonoscopy.
Figure 3
Figure 3
Follow-up abdominoplevic CT scan revealing a suspicious enlarged 2 cm mesenteric lymph node and PET-scan showing a high FDG uptake of the enlarged mesenteric lymph node.
Figure 4
Figure 4
Hematoxylin and eosin stain, enlarged 20x, lymph node infiltrated with tumor cells and hematoxylin and eosin stain, enlarged 100x, findings suggestive of leiomyosarcoma found within the mesenteric lymph node.
Figure 5
Figure 5
Hematoxylin and eosin stain, enlarged 100x, vascular involvement of the tumor within the mesenteric lymph node.
See this image and copyright information in PMC

References

    1. Cuffy M., Abir F., Longo W. E. Management of less common tumors of the colon, rectum, and anus. Clinical Colorectal Cancer. 2006;5(5):327–337. doi: 10.3816/CCC.2006.n.002. - DOI - PubMed
    1. Meijer S., Peretz T., Gaynor J. J., Tan C., Hajdu S. I., Brennan M. F. Primary colorectal sarcoma. A retrospective review and prognostic factor study of 50 consecutive patients. Archives of Surgery. 1990;125(9):1163–1168. doi: 10.1001/archsurg.1990.01410210089014. - DOI - PubMed
    1. Luna-Perez P., Rodriguez D. F., Lujan L., et al. Colorectal sarcoma: analysis of failure patterns. Journal of Surgical Oncology. 1998;69(1):36–40. doi: 10.1002/(sici)1096-9098(199809)69:1<36::aid-jso7>3.0.co;2-l. - DOI - PubMed
    1. Thiels C. A., Bergquist J. R., Krajewski A. C., et al. Outcomes of primary colorectal sarcoma: a National Cancer Data Base (NCDB) review. Journal of Gastrointestinal Surgery. 2017;21(3):560–568. doi: 10.1007/s11605-016-3347-0. - DOI - PubMed
    1. Anzai H., Nozawa H., Tanaka J., et al. Giant leiomyosarcoma of the rectum with lymph node metastasis: a case report and review of the literature. International Journal of Surgery Case Reports. 2017;34:27–31. doi: 10.1016/j.ijscr.2017.03.008. - DOI - PMC - PubMed

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