Anaphylaxis as a Rare Side Effect of Ketorolac; a Case Report
- PMID: 32259118
- PMCID: PMC7130438
Anaphylaxis as a Rare Side Effect of Ketorolac; a Case Report
Abstract
Anaphylaxis is a life-threatening systemic allergic hypersensitivity reaction that may potentially be triggered after the administration of any drug. Our case was a 51-year-old man with the history of mild pain in his flanks since the night before he was admitted to our hospital. The patient was diagnosed with urolithiasis and admitted to the emergency department. He developed anaphylaxis after intravenous injection of 30 mg ketorolac. Allergic reactions to non-steroidal anti-inflammatory drugs (NSAIDs) such as ketorolac are rare; nonetheless, they can be life-threatening and should be carefully monitored.
Keywords: Adverse Drug Reaction; Anaphylaxis; Drug Hypersensitivity Syndrome; NSAIDs; Ketorolac.
References
-
- Cabassi A, Tedeschi S, Perlini S, Verzicco I, Volpi R, Gonzi G, et al. Non-steroidal anti-inflammatory drug effects on renal and cardiovascular function: from physiology to clinical practice. European journal of preventive cardiology. 2019:2047487319848105. - PubMed
-
- Mallinson TE. A review of ketorolac as a prehospital analgesic. Journal of Paramedic Practice. 2017;9(12):522–6.
-
- Cerreta AJ, Masterson CA, Lewbart GA, Dise DR, Papich MG. Pharmacokinetics of ketorolac in wild Eastern box turtles (Terrapene carolina carolina) after single intramuscular administration. Journal of veterinary pharmacology and therapeutics. 2019;42(2):154–9. - PubMed
-
- Oliva A, De FG, Arena V, Fucci N, Pascali VL, Navarra P. Death due to anaphylactic shock secondary to intravenous self-injection of Toradol: a case report and review of the literature. Clinical toxicology (Philadelphia, Pa) 2007;45(6):709–13. - PubMed
-
- Scala E, Giani M, Pirrotta L, Guerra EC, Locanto M, De Pità O, et al. Selective severe anaphylactic reaction due to ketorolac tromethamine without nonsteroidal anti-inflammatory drug intolerance. Journal of Allergy and Clinical Immunology. 2001;107(3) - PubMed
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