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. 2020 Apr 3;10(4):620.
doi: 10.3390/ani10040620.

A Meta-analysis Describing the Effects of the Essential oils Blend Agolin Ruminant on Performance, Rumen Fermentation and Methane Emissions in Dairy Cows

Alejandro Belanche  1 , Charles J Newbold  2 , Diego P Morgavi  3 , Alex Bach  4   5 , Beatrice Zweifel  6 , David R Yáñez-Ruiz  1
Affiliations

A Meta-analysis Describing the Effects of the Essential oils Blend Agolin Ruminant on Performance, Rumen Fermentation and Methane Emissions in Dairy Cows

Alejandro Belanche et al. Animals (Basel). .

Abstract

There is an increasing pressure to identify feed additives which increase productivity or decrease methane emissions. This paper aims to elucidate the effects of supplementing a specific essential oils blend Agolin® Ruminant on the productivity of dairy cows in comparison to non-treated animals. A total of 23 in vivo studies were identified in which Agolin was supplemented at 1 g/d per cow; then a meta-analysis was performed to determine the response ratio on milk yield, rumen fermentation, methane emissions and health. Results indicated that an adaptation period of at least 4 weeks of treatment is required. Whereas short-term studies showed minor and inconsistent effects of Agolin, long-term studies (>4 weeks of treatment) revealed that Agolin supplementation increases milk yield (+3.6%), fat and protein corrected milk (+4.1%) and feed efficiency (+4.4%) without further changes in milk composition and feed intake. Long-term treatment also decreased methane production per day (-8.8%), per dry matter intake (-12.9%) and per fat and protein corrected milk yield (-9.9%) without changes in rumen fermentation pattern. In conclusion, despite the mode of action is still unclear and the small number of studies considered, these findings show that Agolin represents an encouraging alternative to improve productivity in dairy cows.

Keywords: dairy cows; essential oils; meta-analysis; methane; milk yield.

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Conflict of interest statement

Author B.Z. was employed by the company Agolin SA but had no role in the design, execution, interpretation, or writing of the meta-analysis. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flow diagram of all of the records searched and included in the meta-analysis.
Figure 2
Figure 2
Funnel plot for all studies included in the meta-analysis of milk yield (n = 23) in order to detect bias between published and unpublished studies (A) or between experimental designs (B). Triangles represent the median Response Ratio (R) and a range equivalent to two standard deviations. If no publication bias is present, the data-points will be organized symmetrically.
Figure 3
Figure 3
Effect of supplementing an essential oil blend (1 g/d per cow) to lactating dairy cows on the weekly fat and protein corrected milk yield (FPCM) based on 15 studies. The effect was expressed as a percentage of change respect to non-supplemented cows.
See this image and copyright information in PMC

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