Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Aug;21(5):713-719.
doi: 10.1111/pedi.13016. Epub 2020 Apr 29.

Increasing incidence of type 1 diabetes among Hong Kong children and adolescents: The Hong Kong Childhood Diabetes Registry 2008 to 2017

Joanna Yuet-Ling Tung  1   2 , Elaine Yin-Wai Kwan  3 , Betty Wai-Man But  4 , Wilfred Hing-Sang Wong  1 , Antony Chun-Cheung Fu  5 , Gloria Pang  5 , Jennifer Wing-Yan Tsang  6 , Ho-Chung Yau  6 , Kiran Belaramani  7 , Lap-Ming Wong  7 , Shirley Man-Yee Wong  4 , Priscilla Lo  8 , Kwok-Leung Ng  8 , Wilson Kwan-Yee Yeung  3 , Kwong-Tat Chan  3 , Angela Mo-Kit Chan  9 , Sammy Wai-Chun Wong  9 , Ming-Kut Tay  10 , Jacky Chung  11 , Ching-Yin Lee  11 , Yuen-Yu Lam  12 , Pik-To Cheung  1
Affiliations

Increasing incidence of type 1 diabetes among Hong Kong children and adolescents: The Hong Kong Childhood Diabetes Registry 2008 to 2017

Joanna Yuet-Ling Tung et al. Pediatr Diabetes. 2020 Aug.

Abstract

Objective: The incidence of childhood-onset type 1 diabetes (T1D) has been reported to be rising but there is also evidence that it has been attenuated in recent years. We described the time trends and the incidence of T1D in children in Hong Kong from 2008 to 2017 and compared with the previous local registry in 1997 to 2007.

Methods: Data were extracted from the Hong Kong Childhood Diabetes Registry, which was established in 2016. It consists of a retrospective registry (including all childhood diabetes diagnosed in 2008 to 2015) and a prospective registry (including all T1D children diagnosed from 2016 onwards). All T1D children diagnosed at the age of less than 18 years from 1 January 2008 to 31 December 2017 and managed in the public system were included in this study.

Results: For the incident years in the 2008 to 2017 period, a total of 498 children with T1D was identified. The crude incidence rate was 4.3 per 100 000 person/year (95% confidence interval 3.96-4.72), which was much higher than the last registry of 2.2 per 100 000 persons/year. Using general linear model, the increment is statistically significant (P = .02). When compared to the last registry, the rate of increment had attenuated, with annual increment in crude incidence in the two periods for T1D <15 years changing from 4.3% to 3.5% (P = .02).

Conclusions: The incidence of T1D children increased significantly in the past two decades in Hong Kong, but the rate of increase had attenuated in recent years.

Keywords: Childhood Diabetes Registry; Hong Kong; epidemiology; incidence; pediatrics; type 1 diabetes mellitus.

PubMed Disclaimer

References

REFERENCES

    1. Wu HB, Zhong JM, Hu RY, et al. Rapidly rising incidence of type 1 diabetes in children and adolescents aged 0-19 years in Zhejiang, China, 2007 to 2013. Diabet Med. 2016;33(10):1339-1346. https://doi.org/10.1111/dme.13010.
    1. Negrato CA, Lauris JRP, Saggioro IB, et al. Increasing incidence of type 1 diabetes between 1986 and 2015 in Bauru, Brazil. Diabetes Res Clin Pract. 2017;127:198-204. https://doi.org/10.1016/j.diabres.2017.03.014.
    1. Kim JH, Lee CG, Lee YA, Yang SW, Shin CH. Increasing incidence of type 1 diabetes among Korean children and adolescents: analysis of data from a nationwide registry in Korea. Pediatr Diabetes. 2016;17(7):519-524. https://doi.org/10.1111/pedi.12324.
    1. Radosevic B, Bukara-Radujkovic G, Miljkovic V, Pejicic S, Bratina N, Battelino T. The incidence of type 1 diabetes in Republic of Srpska (Bosnia and Herzegovina) and Slovenia in the period 1998-2010. Pediatr Diabetes. 2013;14(4):273-279. https://doi.org/10.1111/j.1399-5448.2012.00898.x.
    1. Dahlquist G. Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis. Diabetologia. 2006;49(1):20-24. https://doi.org/10.1007/s00125-005-0076-4.

Publication types

LinkOut - more resources